Retraction to: Cell Death and Disease https://doi.org/10.1038/s41419-020-2448-6, published online 23 April 2020
The Editors-in-Chief have retracted this article after concerns were raised about image irregularities. Further investigation by the publisher found the below concerns to be valid. Additionally, the authors failed to provide raw data and evidence for ethics approval for this study.
The Editors-in-Chief therefore no longer have confidence in the results and conclusions present in this article.
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Partial image overlap between Figure 2A (sh. NANOG, SCC-15 CD44+ cells) and Figure 4G, Migration (SCC-25 CD44+ cells, sh.ERK1/2)
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Image overlap between Figure 2E (sh.SCr, SCC-15 CD44+ cells) and Figure 3C (SK-LMS-1, Spheroids) of [1]
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Image overlap between Figure 2E (sh.SCr, SCC-25 CD44+ cells) and Figure 3C (HT1 080, Spheroids) of [1]
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Multiple image overlaps between Figure 4H, immunofluorescent images and Figure 1D (SNU-668, Spheroids +) of [2]
Kun Huang agrees to retraction. None of the remaining authors have responded to any correspondence from the publisher about this retraction.
References
Chang KK, Yoon C, Yi BC, Tap WD, Simon MC, Yoon SS. Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas. Oncogenesis. 2018;7:47. https://doi.org/10.1038/s41389-018-0059-1.
Yoon C, Cho SJ, Aksoy BA, Park DJ, Schultz N, Ryeom SW, et al. Chemotherapy resistance in diffuse-type gastric adenocarcinoma is mediated by RhoA activation in cancer stem-like cells. Clin Cancer Res. 2016;22:971–83. https://doi.org/10.1158/1078-0432.CCR-15-1356.
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Huang, C., Yoon, C., Zhou, XH. et al. Retraction Note: ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomas. Cell Death Dis 15, 219 (2024). https://doi.org/10.1038/s41419-024-06608-7
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DOI: https://doi.org/10.1038/s41419-024-06608-7
