Despite experimental and mechanistic data suggesting circadian disruption’s role in carcinogenesis, mixed findings from epidemiological investigations of artificial light at night and cancer risk in the general population are difficult to interpret due to exposure assessment limitations. It will be important for future studies to assess and validate individual-level exposures, ideally over the lifetime.
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The author would like to thank Drs. Mary Ward and Debra Silverman, and Ms. Danielle Medgyesi for their thoughtful comments and suggestions.
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This work was supported by the Intramural Research Program of the National Institutes of Health, National Cancer Institute, Division of Cancer Epidemiology and Genetics.
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Jones, R.R. Exposure to artificial light at night and risk of cancer: where do we go from here?. Br J Cancer 124, 1467–1468 (2021). https://doi.org/10.1038/s41416-020-01231-7