Sir, I read with interest the recent correspondence in the BDJ entitled 'Rethinking e-smoking' by R. Lee.1

It would be worth mentioning that in addition to vapourised nicotine, e-cigarette aerosol contains particles of an ultrafine nature which may be inhaled into the deeper portions of the lungs, diacetyl flavouring recognised as a causative agent for serious lung disease, carcinogenic chemicals, organic compounds (volatile) and heavy metals.2

Moreover, consumers might not be aware of what their product contains and certain 'zero percent nicotine' products have been evidenced to actually possess nicotine content.3

Further, it is also relevant to ask patients what kind of substances they have used with their vaping product as these may include THC or CBD.4