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An “impossible” harvest–GCSF-induced immune thrombocytopenia in an autologous stem cell transplant recipient with multiple myeloma

Bone Marrow Transplantation volume 56, pages 1737–1739 (2021)Cite this article

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Dear Editor,

Over 300 drugs have been known to date to cause drug-induced immune thrombocytopenia (DITP). It is characterized by a drop in platelets after 5–10 days of drug, recovery after discontinuation, and simulation of thrombocytopenia with re-challenge [1].

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Fig. 1: Variation in the platelet count before and after first and second GCSF peripheral stem cell harvest.

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Acknowledgements

We acknowledge all the staff of Department of Hematology and BMT unit, Rajiv Gandhi Cancer Institute and Research Centre for providing the support in conducting the study.

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  1. Sumeet Prakash Mirgh

    Present address: Adult Hematolymphoid and BMT Unit, Tata Memorial Hospital ACTREC and Homi Bhabha National Institute, Mumbai, India

Authors and Affiliations

  1. Department of Hematology and Bone Marrow Transplant Unit, Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India

    Jyotsna Kapoor, Vishvdeep Khushoo, Ambar Garg, Faran Naim, Niharika Bhatia, Bhaarat Folbs, Pallavi Mehta, Rayaz Ahmed, Narendra Agrawal, Dinesh Bhurani & Sumeet Prakash Mirgh

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  1. Jyotsna Kapoor
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Contributions

J.K. collected the data and wrote the paper, S.P.M. conceptualized, wrote few portions of paper, and revised the paper, V.K., A.G, F.N., N.B., P.M., N.A., R.A., and D.B. critically reviewed the paper and revised the paper.

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Correspondence to Sumeet Prakash Mirgh.

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The authors declare no competing interests.

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The study has been approved by the Institutional Review Board of our Centre.

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Signed patient permission to publish the case report has been taken from the patient.

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Kapoor, J., Khushoo, V., Garg, A. et al. An “impossible” harvest–GCSF-induced immune thrombocytopenia in an autologous stem cell transplant recipient with multiple myeloma. Bone Marrow Transplant 56, 1737–1739 (2021). https://doi.org/10.1038/s41409-021-01256-3

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