Editorial Expression of Concern to: Oncogene https://doi.org/10.1038/onc.2008.6, published online 04 February 2008
The Editors-in-Chief would like to alert the readers that following the Correction [1] of this article [2] to address the concerns raised regarding the western blot loading controls presented in Figs. 4c and 7a, further issues have been noted:
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The western blot loading controls presented in Figs. 4d and 7c appear highly similar.
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The U6 panel of Fig. 3b appears highly similar to the U6 panel of Fig. 4c of another article from the same author group that was submitted and published within a similar time frame [3].
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The western blot loading controls presented in Fig. 5b and the originally published version of Fig. 7a appear highly similar to the control lanes 1 and 2 (flipped horizontally) of Fig. 3a of [4], which as also submitted and published within a similar time frame.
The authors have stated that the images used in the other articles [3, 4] are incorrect, and are issuing Corrections to replace them with the appropriate data. However, due to the number of concerns raised, readers are advised to interpret the presented data with caution.
M. Garofalo has stated on behalf of all authors that they do not agree to this editorial expression of concern.
References
Garofalo M, Quintavalle C, Di Leva G, Zanca C, Romano G, Taccioli C, et al. Correction: MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer. Oncogene. 2021;40:1204–1204. https://doi.org/10.1038/s41388-020-01608-1
Garofalo M, Quintavalle C, Di Leva G, Zanca C, Romano G, Taccioli C, et al. MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer. Oncogene. 2008;27:3845–55. https://doi.org/10.1038/onc.2008.6
Garzon R, Garofalo M, Martelli MP, Briesewitz R, Wang L, Fernandez-Cymering C, et al. Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin. Proc Natl Acad Sci USA. 2008;105:3945–50. https://doi.org/10.1073/pnas.080013510
Romano G, Briguori C, Quintavalle C, Zanca C, Rivera NV, Colombo A, et al. Contrast agents and renal cell apoptosis. Eur Heart J. 2008;29:2569–76. https://doi.org/10.1093/eurheartj/ehn197
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Garofalo, M., Quintavalle, C., Di Leva, G. et al. Editorial Expression of Concern: MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer. Oncogene 43, 1075 (2024). https://doi.org/10.1038/s41388-024-02989-3
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DOI: https://doi.org/10.1038/s41388-024-02989-3