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In-hospital mortality and length of hospital stay in infants requiring tracheostomy with bronchopulmonary dysplasia

Journal of Perinatology (2023)Cite this article

Subjects

Abstract

Purpose

To investigate in-hospital mortality and hospital length of stay (LOS) in infants requiring tracheostomy with bronchopulmonary dysplasia (BPD).

Methods

We explored the correlation between tracheostomy with in-hospital mortality and LOS in infant patients hospitalized with BPD, using the data from Nationwide Inpatient Sample between 2008 and 2017 in the United States. In-hospital mortality and LOS was compared in patients who underwent tracheostomy with those patients who did not after propensity-score matching.

Results

A total of 10,262 children ≤2 years old hospitalized with BPD, 847 (8%) underwent tracheostomy, and 821 patients underwent tracheostomy were matched with 1602 patients without tracheostomy. Tracheostomy group was correlated with higher in-hospital mortality(OR(95%CI):2.98(2.25–3.95)) and prolonged LOS(absolute difference(95%CI):97.0(85.6–108.4)).

Conclusions

Tracheostomy was correlated with increased in-hospital mortality and prolonged LOS. Such information may contribute to better decision-making process between clinicians and parents regarding tracheostomy to manage parent expectations, as well as better interdisciplinary teamwork.

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Fig. 1: Study cohort of infant patients with bronchopulmonary dysplasia.

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Data availability

The data we used in the study is publicly available.

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Acknowledgements

The authors thank Dr. Xiaotian Chen (Children’s Hospital of Fudan University, Shanghai, China) for reviewing the manuscript.

Funding

This work is supported by the Three-Year Action Plan for Strengthening Public Health System in Shanghai (2020–2022) Subject Chief Scientist (GWV-10.2-XD05), Pilot Program of Naval Medical University (Cheng WU), National Key Research and Development Program of China (2021YFC2701800, 2021YFC2701805).

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Author notes

  1. These authors contributed equally: Ronghui Zhu, Yetao Xu, Yuchen Qin.

Authors and Affiliations

  1. Department of Military Health Statistics, Naval Medical University, Shanghai, China

    Ronghui Zhu, Yuchen Qin, Jinfang Xu, Rui Wang, Shengyong Wu, Yi Cheng, Xiao Luo, Yaoyong Tai, Chenxin Chen, Jia He & Cheng Wu

  2. Department of Rehabilitation, Children’s Hospital of Fudan University, Shanghai, China

    Yetao Xu & Sujuan Wang

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  1. Ronghui Zhu
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Contributions

RZ and YX designed the work. RZ, YX and YQ drafted the work. JX, RW, SW, YC, XL, YT, CC and JH critically reviewed the work for intellectual content. SW and CW were the guarantors. All authors approved the final manuscript.

Corresponding authors

Correspondence to Sujuan Wang or Cheng Wu.

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Competing interests

The authors declare no competing interests.

Ethics approval

Because the NIS is a de-identified inpatient health-care database for public availability, our study was exempted by the Committee on Ethics of Medical Research at Naval Medical University.

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Zhu, R., Xu, Y., Qin, Y. et al. In-hospital mortality and length of hospital stay in infants requiring tracheostomy with bronchopulmonary dysplasia. J Perinatol (2023). https://doi.org/10.1038/s41372-023-01840-z

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  • DOI: https://doi.org/10.1038/s41372-023-01840-z

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