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Laparotomy or peritoneal drainage in preterm infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis?

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References

  1. Blakely ML, Tyson JE, Lally KP, Hintz SR, Eggleston B, Stevenson DK, et al. Initial laparotomy versus peritoneal drainage in extremely low birthweight infants with surgical necrotizing enterocolitis or isolated intestinal perforation: a multicenter randomized clinical trial. Ann Surg. 2021;274:e370–80.

    Article  PubMed  Google Scholar 

  2. Aschner JL, Deluga KS, Metlay LA, Emmens RW, Hendricks-Munoz KD. Spontaneous focal gastrointestinal perforation in very low birth weight infants. J Pediatr. 1988;113:364–67.

    Article  CAS  PubMed  Google Scholar 

  3. Wadhawan R, Oh W, Hintz SR, Blakely ML, Das A, Bell EF, et al. Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis. J Perinatol. 2014;34:64–70.

    Article  PubMed  Google Scholar 

  4. Rees CM, Eaton S, Kiely EM, Wade AM, McHugh K, Pierro A. Peritoneal drainage or laparotomy for neonatal bowel perforation? A randomized controlled trial. Ann Surg. 2008;248:44–51.

    Article  PubMed  Google Scholar 

  5. Moss RL, Dimmitt RA, Barnhart DC, Sylvester KG, Brown RL, Powell DM, et al. Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation. N. Engl J Med. 2006;354:2225–34.

    Article  CAS  PubMed  Google Scholar 

  6. Blakely ML, Tyson JE, Lally KP, McDonald S, Stoll BJ, Stevenson DK, et al. Laparotomy versus peritoneal drainage for necrotizing enterocolitis or isolated intestinal perforation in extremely low birth weight infants: outcomes through 18 months adjusted age. Pediatrics. 2006;117:e680–7.

    Article  PubMed  Google Scholar 

  7. Walsh M, Perkovic V, Manns B, Srinathan S, Meade MO, Devereaux P, et al. Therapy (Randomized Trials). In: Guyatt G, Rennie D, Meade MO, Cook DJ editors. Users’ Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed. McGraw Hill; 2015. Accessed Dec 21 2022

  8. Wang X, Piantadosi S, Le-Rademacher J, Mandrekar SJ. Statistical considerations for subgroup analyses. J Thorac Oncol 2021;16:375–80.

    Article  PubMed  Google Scholar 

  9. Doyle LW, Halliday HL, Ehrenkranz RA, Davis PG, Sinclair JC. Impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk for chronic lung disease. Pediatrics. 2005;115:655–61.

    Article  PubMed  Google Scholar 

  10. Lilford RJ, Thornton JG, Braunholtz D. Clinical trials and rare diseases: a way out of a conundrum. BMJ. 1995;311:1621–25.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Spiegelhalter DJ, Laurence S, Freedman, Mahesh KB. Bayesian approaches to randomized trials.J R Stat Soc Ser A (Stat Soc). 1994;157:357–416. https://doi.org/10.2307/2983527.

    Article  Google Scholar 

  12. Lilford RJ, Johnson N. The alpha and beta errors in randomized trials. N. Engl J Med. 1990;322:780–81.

    Article  CAS  PubMed  Google Scholar 

  13. Amrhein V, Greenland S, McShane B. Scientists rise up against statistical significance. Nature. 2019;567:305–7.

    Article  CAS  PubMed  Google Scholar 

  14. Kelter R. Bayesian alternatives to null hypothesis significance testing in biomedical research: a non-technical introduction to Bayesian inference with JASP. BMC Med Res Methodol. 2020;20:142.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Zampieri FG, Casey JD, Shankar-Hari M, Harrell FE Jr, Harhay MO. Using bayesian methods to augment the interpretation of critical care trials. an overview of theory and example reanalysis of the alveolar recruitment for acute respiratory distress syndrome trial. Am J Respir Crit Care Med. 2021;203:543–52.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Laptook AR, Shankaran S, Tyson JE, Munoz B, Bell EF, Goldberg RN, et al. Effect of therapeutic hypothermia initiated after 6 h of age on death or disability among newborns with hypoxic-ischemic encephalopathy: a randomized clinical trial. JAMA. 2017;318:1550–60.

    Article  PubMed  PubMed Central  Google Scholar 

  17. van de Schoot R, Kaplan D, Denissen J, Asendorpf JB, Neyer FJ, van Aken MAG. A gentle introduction to bayesian analysis: applications to developmental research. Child Dev. 2014;85:842–60.

    Article  PubMed  Google Scholar 

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Acknowledgements

The Journal Club is a collaboration between the American Academy of Pediatrics - Section of Neonatal Perinatal Medicine and the International Society for Evidence-Based Neonatology (EBNEO.org)

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ER and FJ conceptualized, drafted the initial manuscript, and reviewed and approved the final draft of the manuscript. RB and SM mentored, reviewed, revised, and approved the final version of the manuscript.

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Correspondence to Ramachandra Bhat.

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Rivero, E., Javed, F., Manzar, S. et al. Laparotomy or peritoneal drainage in preterm infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis?. J Perinatol 44, 146–150 (2024). https://doi.org/10.1038/s41372-023-01770-w

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