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Systematic ultrasound examinations in neonates admitted to NICU: evolution of portal vein thrombosis

Journal of Perinatology volume 38, pages 1359–1364 (2018)Cite this article

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Abstract

Objective:

The aim of the study was to better describe incidence, risk factors, and the natural evolution of neonatal portal vein thrombosis (PVT).

Study design:

One hundred and twenty-three premature newborns or with birth weight <1.5 kg were prospectively included in a single center during a one-year period. Three systematic abdominal ultrasound examinations at day 3, day 10, and day 45 (and 1 year in case of persistent PVT) were performed. Clinical and biological data were recorded.

Results:

Seventy neonates (57%) had three normal US examinations. Fifty-three neonates (43%) had a clinical and biological asymptomatic left PVT. No right or extrahepatic portal venous thrombosis was observed. Umbilical vascular catheter (UVC) was removed in case of PVT. No anticoagulation therapy was required. No risk factor was significantly associated with PVT. At 1 year of follow-up, five infants had persistent isolated left PVT (4%).

Conclusion:

A spontaneous favorable evolution of left PVT occurred in more than of 95%.

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Acknowledgements

The authors thank John Sheath for English language assistance.

Author Contributions

BM, MC, AB, and DS conceptualized and designed the study, recruited patients, drafted the initial manuscript, and approved the final manuscript as submitted. MC and AF designed the data collection instruments, coordinated and supervised data collection, recruited patients for the study, and drafted the initial manuscript. CS-T, LM, AF, GF, PB, and ES recruited patients for the study, reviewed and revised the manuscript, and approved the final manuscript as submitted. BM and DS designed the data collection instruments, recruited patients for the study, coordinated and supervised data collection, critically reviewed the manuscript, and approved the final manuscript as submitted. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

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Authors and Affiliations

  1. Department of Pediatric Radiology, Clocheville Hospital, CHRU, 49 Boulevard Beranger, Tours, France

    Mathieu Cabannes, Catherine Sembély-Taveau, Luciano Morales, Dominique Sirinelli & Baptiste Morel

  2. Department of Neonatology, Clocheville Hospital, CHRU, 49 Boulevard Beranger, Tours, France

    Antoine Bouissou, Géraldine Favrais, Amélie Favreau & Elie Saliba

  3. Department of Radiology, Bretonneau Hospital, CHRU, 10 Boulevard Tonnellé, Tours, France

    Philippe Bertrand

  4. Francois Rabelais University, Faculty of Medicine, Tours, France

    Philippe Bertrand, Elie Saliba, Dominique Sirinelli & Baptiste Morel

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  1. Mathieu Cabannes
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  2. Antoine Bouissou
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  4. Catherine Sembély-Taveau
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Correspondence to Baptiste Morel.

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Cabannes, M., Bouissou, A., Favrais, G. et al. Systematic ultrasound examinations in neonates admitted to NICU: evolution of portal vein thrombosis. J Perinatol 38, 1359–1364 (2018). https://doi.org/10.1038/s41372-018-0132-9

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  • DOI: https://doi.org/10.1038/s41372-018-0132-9

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