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Epidemiology and Population Health

Years of life with and without limitation in physical function and in activities of daily living by body mass index among older adults

Abstract

Background

While older adults with pre-obesity and Class I obesity have similar or lower mortality risk versus those with normal weight, a heavier body mass index (BMI) may not translate into more healthy life years. Utilizing longitudinal data on 3452 older (≥60 years) Singaporeans, we assessed the association between BMI and years of remaining life overall with and without limitation in physical function and in activities of daily living (ADLs).

Methods

Difficulty in any of nine tasks involving upper or lower extremities was considered as limitation in physical function, and health-related difficulty in any basic ADL or instrumental ADL as limitation in ADLs. We utilized multistate life tables, including BMI as a time-varying covariate.

Results

At age 60, life expectancy (LE) was similar for those with normal weight, pre-obesity and obesity. However, those with obesity, versus normal weight, had 6.3 [95% confidence interval: 3.4–9.2] more years with limitation in physical function and 4.9 [3.4–6.5] less years without limitation in physical function. Those with pre-obesity, versus normal weight, also had 3.7 [1.9–5.3] more years with limitation in physical function. The same pattern across BMI categories was observed for years of life with and without limitation in ADLs. In stratified analyses, similar associations of BMI with years of life with and without limitation in physical function and in ADLs were observed across gender, ethnicity, and educational status.

Conclusions

The increasing global prevalence of obesity may result in an increase in years of life with limitation in physical function and in ADLs at older ages. Older adults, their families and healthcare systems should be cognizant of this issue.

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Code availability

The dataset and IMaCh code can be requested from the corresponding author.

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Acknowledgements

Waves 1, 2 and 3 of the Panel on Health and Ageing of Singaporean Elderly (PHASE) were funded or supported by the following sources: Ministry of Social and Family Development, Singapore; Singapore Ministry of Health’s National Medical Research Council under its Singapore Translational Research Investigator Award “Establishing a Practical and Theoretical Foundation for Comprehensive and Integrated Community, Policy and Academic Efforts to Improve Dementia Care in Singapore” (NMRC-STAR-0005-2009), and its Clinician Scientist – Individual Research Grant - New Investigator Grant “Singapore Assessment for Frailty in Elderly-Building upon the Panel on Health and Aging of Singaporean Elderly” (NMRC-CNIG-1124-2014); and Duke-NUS Geriatric Research Fund.

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Correspondence to Rahul Malhotra.

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Tareque, M.I., Saito, Y., Chan, A. et al. Years of life with and without limitation in physical function and in activities of daily living by body mass index among older adults. Int J Obes 43, 2244–2253 (2019). https://doi.org/10.1038/s41366-019-0370-8

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