Vascular intrauterine growth restriction seems to offer only transient protection against neonatal excitotoxic insult, possibly via angiogenesis.

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Purified vessel-specific cell types are suitable for gene expression profiling and functional studies of the ductus arteriosus, and provide important tools for improving our understanding of the complex processes involved in its closure.

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Fetal systemic endotoxinemia induced myocardial inflammation by activating toll-like receptors 2 and 4. Subsequent cardiac dysfunction seems not to be mediated via cardiac inducible nitric oxide synthase.

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Investigators created a novel animal model that seems to reflect both the hemodynamic and electrophysiological characteristics of repaired tetralogy of Fallot, and can be applied to evaluate the risk of post-operative ventricular arrhythmias.

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In a piglet model of hemorrhagic shock, intrathoracic pressure regulation treatment improved mean arterial pressures, cardiac index, and 24-hour survival rates.

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Infant abdominal adipose tissue and liver lipid content increase with increasing maternal body mass index across the normal range. These effects may be initiating determinants of a life-long trajectory leading to adverse metabolic health.

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