Abstract
Background: A recent advance in ventilator system introduced the Puritan Bennett 840™ Ventilators (PB840) were introduced in the BUHMC during 2003. We observed its outcome in very low birth weight (VLBW) infants.
Objective: To compare the neonatal outcome of VLBW infants between two time periods when different ventilators were used.
Design/Methods: During 01/01/2002∼4/31/2003 the BP200 and Bear Cub ventilators were used in the NICU. After that the PB840 with a separate nasal CPAP machine were used during 05/31/2003∼12/31/2003. Neonatal data for 109 infants with a birth weight less than 1500gm (excluding L&D deaths) were collected from medical records and respiratory department.
Results: Between two periods, the use of prenatal and postnatal steroids, birth weight, respiratory distress syndrome(RDS), patent ductus arteriosus (PDA), ventilator days (including ventilator and CPAP days), oxygen requirement at 28 days & discharge, length of stay, pneumothorax, intraventricular hemorrhage (IVH), necrotizing enterocolitis (NEC), sepsis, and death were not significantly different. However, there was a significantly higher incidence of oxygen requirement at 36 weeks of postmenstural age in period of PB840 use than the previous period with other ventilators (18% vs. 37%, p=.03).
Comparison of the neonatal outcome between two periods: n=109 (%) Table 1
Conclusions: During the period of PB840 use, VLBW infants had a significantly higher incidence of chronic lung disease. It may be due to less aggressive management for chronic lung disease or inefficient assist ventilation of PB 840. For a better respiratory care in neonate further studies in ventilator and nasal CPAP machine are needed.
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V, G., R, K., D, J. et al. 32 Comparison of Neonatal Outcome of Different Ventilators in Very Low Birth Weight Infants.. Pediatr Res 58, 821 (2005). https://doi.org/10.1203/00006450-200510000-00062
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DOI: https://doi.org/10.1203/00006450-200510000-00062