Age > 10 days has been considered as an exclusion criteria for neonatal ECMO because of the concern regarding decreased survival and risk of bronchopulmonary dysplasia (BPD). However, since there is paucity of outcome data in this patient population, we analyzed neonatal ECMO registry data of ELSO from April 1988 thru March 1995 to determine the effect of age at initiation of ECMO on mortality (death prior to discharge), and ECMO outcome namely duration of ECMO, need for post ECMO ventilatory support, BPD and length of stay (LOS). Patients with congenital diaphragmatic hernia were excluded from this analysis.. Table
Conclusions: 1]. The increased mortality and morbidity in neonates going on ECMO at >7days of age must be taken into consideration since newer therapies such as nitric oxide being introduced in the management of pulmonary hypertension could delay initiation of ECMO. 2]. Exclusion criterion regarding age >10 days at initiation of ECMO may need to be reconsidered in light of this data which shows a surprisingly high survival rate in this patient population.
*Mean(±SD) **ChiSquare ***ANOVA
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(Sponsored by W. B. Pittard, III, MD)
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Purohit, D., Cantey, J., Southgate, W. et al. AGE AT INITIATION OF EXTRACORPOREAL MEMBRANE OXYGENATION (ECMO) AND OUTCOME IN NEONATES. ANALYSIS OF REGISTRY DATA OF THE EXTRACORPOREAL LIFE SUPPORT ORGANIZATION (ELSO). † 1421. Pediatr Res 39 (Suppl 4), 239 (1996). https://doi.org/10.1203/00006450-199604001-01444
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DOI: https://doi.org/10.1203/00006450-199604001-01444
