ESR is a useful test in the dx of infections in immuno competent host. Pattern of changes and baseline value among HIV patients have not been studied. We determined ESR on 24 patients with HIV (mean age 6 yrs) including 13 males during stable non symptomatic phase in the clinic with standard Westergren method. Dx of HIV was based on standard tests and CD4/CD8 ratio& PCR. A second ESR value was determined during hospitalization for various infections including pneumonia, otitis media, UTI, etc. Percent changes in ESR values were correlated with T cell counts and viral load. Results are presented. List Table

Table 1

Mean baseline ESR of 33 was higher as compared to 20 mm the upper limit of normal in normal subjects. Mean ESR increased significantly with infections(P<0.005). Percent ↑ from baseline was higher in males but insignificantly. Baseline values &%↑ had no significantly correlation with sex, CD4,CD8 and viral load.

We conclude that 1) ESR value of >20mm/1hr should not be used in the diagnosis of bacterial infection. 2) Value of > (33+ISD=47) would be more practical as upper normal limit in patients with HIV.