Trace Elements (Zinc, Cobalt, Selenium, Rubidium, Bromine, Gold) in Human Placenta and Newborn Liver at Birth

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Summary: Concentrations of zinc, cobalt, selenium, rubidium, bromium, and gold have been determined by neutron activation analysis in 18 placenta) and 6 liver tissue samples at birth. Their respective mean concentrations ± standard deviations (parts per million) were 58 ± 10, 0.060 ± 0.036, 1.90 ± 0.41, 14.0 ± 3.5, 26.9 ± 14.3, and 0.31 ± 0.14 in placenta, and 651 ± 257, 0.156 ± 0.077, 4.52 ± 1.96, 9.2 ± 3.7, 11.2 ± 4.1, and 0.12 ± 0.06 in liver tissue. Thus, we observed that the mean concentrations of essential trace elements (zinc, cobalt, and selenium) were significantly higher in liver than in placenta, whereas the nonessential trace elements (rubidium, bromium, and gold) were found in significantly higher concentrations in placenta than in liver tissue.

Speculation: The observed Difference in the distribution pattern of the stutdied trace elements in placenta and liver tissues should be extended to other essential and nonessential trace elements. it would also be intresting to study the distrubution pattern of trace elements in various pathologic conditions of the fetus.

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Correspondence to D Alexiou.

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Alexiou, D., Grimanis, A., Grimani, M. et al. Trace Elements (Zinc, Cobalt, Selenium, Rubidium, Bromine, Gold) in Human Placenta and Newborn Liver at Birth. Pediatr Res 11, 646–648 (1977). https://doi.org/10.1203/00006450-197705000-00005

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Keywords

  • Liver
  • newborn
  • plnccnta
  • trace elements
  • pregnancy

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