Abstract
Porous spherical particles of chitosan were prepared by conventional suspension evaporation with modification. Aqueous chitosan solution was dispersed in decahydronaphthalene as the suspension medium with a nonionic surfactant as the emulsifier. O/w/o multiple emulsions consisting of aqueous chitosan particles containing decahydronaphthalene and dispersed in decahydronaphthalene were obtained. Chitosan precipitated as insoluble spherical particles by the gradual removal of water with heating. Particle porosity was related to microemulsions formation, the cloud point of the emulsifier and chemical structure of the acid used.
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Adachi, T., Ida, Ji., Wakita, Ma. et al. Preparation of Spherical and Porous Chitosan Particles by Suspension Evaporation with O/W/O Multiple Emulsions. Polym J 31, 319–323 (1999). https://doi.org/10.1295/polymj.31.319
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DOI: https://doi.org/10.1295/polymj.31.319