Abstract
In order to obtain information about the interaction between DNA and poly(L-lysine), calorimetric studies of DNA–poly(L-lysine) solutions prepared by direct mixing were carried out using a batch-type microcalorimeter and a differential scanning calorimeter. Furthermore, to complement this calorimetric data, CD spectra of DNA–poly(L-lysine) solutions were also measured. From the results of the calorimetric and the spectrophotometric measurements, the enthalpies of the interaction between DNA and poly(L-lysine) and the conformational change of DNA accompanied by an interaction between DNA and poly(L-lysine) were estimated to be about 4 and 6 kJ, respectively.
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Fujioka, K., Baba, Y. & Kagemoto, A. Thermal Properties of DNA–Poly(L-lysine) System. Polym J 11, 509–513 (1979). https://doi.org/10.1295/polymj.11.509
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DOI: https://doi.org/10.1295/polymj.11.509