Abstract
The conformational changes of polypeptides associated with the formation of polyelectrolyte complexes were studied as a function of pH for the systems of poly(L-glutamic acid)—poly(ethyleneimine) and poly(L-lysine)—Carboxymethyl cellulose, by means of optical rotatory dispersion and circular dichroism spectroscopies, and potentiometric and turbidimetric measurements. With the poly(L-glutamic acid)—poly(ethyleneimine) system, the pH-induced helix formation of the polypeptide was promoted by the presence of poly(ethyleneimine, while with the poly(L-lysine)—Carboxymethyl cellulose system, the pH-induced coil-to-helix transition was scarcely affected by the presence of carboxymethyl cellulose. These results are interpreted in terms of chain flexibility of the partner polymer of the polypeptide.
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Sato, H., Hayashi, T. & Nakajima, A. The Effect of Polyelectrolyte Complex Formation on pH-Induced Conformational Changes of Polypeptides for Systems of Poly(L-glutamic acid)—Poly(ethyleneimine) and Poly(L-lysine)—Carboxymethyl Cellulose. Polym J 8, 517–523 (1976). https://doi.org/10.1295/polymj.8.517
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DOI: https://doi.org/10.1295/polymj.8.517