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Basic Research

Prostate cancer detection by TURP after repeated negative saturation biopsy in patients with persistent suspicion of cancer: a case–control study on 75 consecutive patients

Prostate Cancer and Prostatic Diseases volume 13, pages 83–86 (2010)Cite this article

Abstract

To evaluate prostate cancer (PCa) detection after repeated negative saturation biopsy, 75 patients, aged 53–78 years, underwent transurethral resection of prostate (TURP) because of persistent suspicion of cancer; median PSA was 11.8 ng ml−1 and 58 men complained lower urinary tract symptoms (LUTS). In 12 (16%) and 3 (4%) men a T1a and T1b PCa was found with median PSA and Gleason score equal to 14.2 vs 23.6 ng ml−1 and 5.6 vs 7 ng ml−1. In case of persistent suspicion of PCa after repeated negative saturation biopsy, TURP may be proposed, aside from the coexistence of LUTS, to rule out a PCa, in younger patients with high PSA values (⩾20 ng ml−1).

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Authors and Affiliations

  1. Department of Urology, Cannizzaro Hospital, Catania, Italy

    P Pepe & F Aragona

  2. Department of Pathology, Cannizzaro Hospital, Catania, Italy

    F Fraggetta, A Galia & G Grasso

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  1. P Pepe
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  2. F Fraggetta
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  3. A Galia
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  4. G Grasso
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  5. F Aragona
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Correspondence to P Pepe.

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Pepe, P., Fraggetta, F., Galia, A. et al. Prostate cancer detection by TURP after repeated negative saturation biopsy in patients with persistent suspicion of cancer: a case–control study on 75 consecutive patients. Prostate Cancer Prostatic Dis 13, 83–86 (2010). https://doi.org/10.1038/pcan.2009.46

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