News & Views | Published:

Molecular basis of HSF regulation

Nature Structural & Molecular Biology volume 23, pages 9395 (2016) | Download Citation

Two structural studies provide new insights into the mechanisms regulating the DNA binding and activation of human HSF family members.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , , & Science 319, 916–919 (2008).

  2. 2.

    Cold Spring Harb. Symp. Quant. Biol. 76, 91–99 (2011).

  3. 3.

    , & Cell 157, 52–64 (2014).

  4. 4.

    , & Trends Cell Biol. 24, 506–514 (2014).

  5. 5.

    , & Nat. Rev. Mol. Cell Biol. 11, 545–555 (2010).

  6. 6.

    , & J. Mol. Biol. 427, 3793–3816 (2015).

  7. 7.

    Heat Shock Factor (Springer Japan, 2016).

  8. 8.

    et al. Cell 150, 549–562 (2012).

  9. 9.

    et al. Proc. Natl. Acad. Sci. USA 110, E3388–E3397 (2013).

  10. 10.

    et al. Mol. Cell. Biol. 35, 11–25 (2015).

  11. 11.

    , , , & Nat. Struct. Mol. Biol. 23, 140–146 (2016).

  12. 12.

    , IV, & Nat. Struct. Mol. Biol. 23, 147–154 (2016).

  13. 13.

    & Nat. Struct. Biol. 6, 464–470 (1999).

  14. 14.

    et al. Mol. Cell. Biol. 23, 5882–5895 (2003).

  15. 15.

    , , , & Science 323, 1063–1066 (2009).

  16. 16.

    et al. Cell 156, 975–985 (2014).

  17. 17.

    , & Mol. Cell. Biol. 31, 4232–4243 (2011).

  18. 18.

    , , & Nature 442, 1050–1053 (2006).

  19. 19.

    & Curr. Opin. Struct. Biol. 10, 110–116 (2000).

  20. 20.

    et al. Mol. Cell 48, 182–194 (2012).

  21. 21.

    et al. Mol. Cell. Biol. 26, 955–964 (2006).

  22. 22.

    et al. J. Biol. Chem. 284, 2435–2447 (2009).

  23. 23.

    & Mol. Cell. Biol. 14, 7592–7603 (1994).

  24. 24.

    et al. Nat. Commun. 6, 6580 (2015).

Download references

Author information

Affiliations

  1. Akira Nakai is at the Department of Biochemistry and Molecular Biology, Yamaguchi University School of Medicine, Ube, Japan.

    • Akira Nakai

Authors

  1. Search for Akira Nakai in:

Competing interests

The author declares no competing financial interests.

Corresponding author

Correspondence to Akira Nakai.

About this article

Publication history

Published

DOI

https://doi.org/10.1038/nsmb.3165

Further reading

Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing