The new crystal structure of the IRF-3 transactivation domain reveals an evolutionarily conserved protein domain whose activity is modulated by phosphorylation controlling oligomerization and protein-protein interactions.
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Moustakas, A., Heldin, CH. The nuts and bolts of IRF structure. Nat Struct Mol Biol 10, 874–876 (2003). https://doi.org/10.1038/nsb1103-874
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DOI: https://doi.org/10.1038/nsb1103-874