The known X-ray crystal structure of a bacterial RNA polymerase together with systematic site-specific protein nucleic acid crosslinking analyses have allowed the determination of the path of DNA and RNA through RNA polymerase.
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We are grateful to R.H. Ebright for valuable discussions.
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Bell, S., Jackson, S. Charting a course through RNA polymerase. Nat Struct Mol Biol 7, 703–705 (2000). https://doi.org/10.1038/78907
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DOI: https://doi.org/10.1038/78907
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