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Forming and inhibiting PRT active sites

Nature Structural Biology volume 6, pages 502–504 (1999)Cite this article

An Erratum to this article was published on 01 July 1999

Abstract

Snapshots of an enzyme at three points along its reaction pathway illustrate the importance of conformational change and frame an argument about reaction mechanism.

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Figure 1: Views of a phosphoribosyltransferase structure.
Figure 2: Ligand binding to the PRT active site at different points in the catalytic cycle.

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Authors and Affiliations

  1. the Department of Biological Sciences, Purdue University, West Lafayette, 47907, Indiana, USA

    Janet L. Smith

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  1. Janet L. Smith
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Smith, J. Forming and inhibiting PRT active sites. Nat Struct Mol Biol 6, 502–504 (1999). https://doi.org/10.1038/9266

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