Lower urinary tract symptoms (LUTS) such as urgency incontinence are a common problem in patients with multiple sclerosis (MS), and can seriously affect the quality of life of these patients. Now, data from a prospective study shows that, in patients with MS who have lesions of the pontine micturition centre (PMC), a greater lesion diameter is positively correlated with weak urinary stream, and urgency incontinence as confirmed using symptom-specific questionnaires. These data suggest that a patient's individual CNS lesion characteristics could be used to predict LUT symptoms.
References
Weissbart, S. J. et al. The impact of pontine disease on lower urinary tract symptoms in patients with multiple sclerosis. Neurourol. Urodyn. http://dx.doi.org/10.1002/nau.22953 (2016)
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Sidaway, P. PMC lesions correlate with LUTS in MS. Nat Rev Urol 13, 125 (2016). https://doi.org/10.1038/nrurol.2016.17
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DOI: https://doi.org/10.1038/nrurol.2016.17