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Prostate cancer

Elective pelvic nodal radiotherapy: is the jury still out?

Elective pelvic nodal irradiation (EPNI) remains a controversial area in prostate cancer management. Two articles published in the International Journal of Radiation, Oncology, Biology and Physics present additional data regarding the benefits of EPNI for patients with high-risk prostate cancer, suggesting that EPNI confers no benefit in overall survival or biochemical-progression-free survival.

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References

  1. Amini, A. et al. Survival outcomes of whole-pelvic versus prostate-only radiotherapy for high risk prostate cancer patients using the National Cancer Data Base. Int. J. Radiat. Oncol. Biol. Phys. http://dx.doi.org/10.1016/j.ijrobp.2015.09.006.

  2. Blanchard, P. et al. Outcome according to elective pelvic radiotherapy in patients with high-risk localized prostate cancer: a secondary analysis of the GETUG 12 Phase III randomized trial. Int. J. Radiat. Oncol. Biol. Phys. http://dx.doi.org/10.1016/j.ijrobp.2015.09.020.

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Correspondence to Juanita Crook.

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Crook, J. Elective pelvic nodal radiotherapy: is the jury still out?. Nat Rev Urol 13, 10–11 (2016). https://doi.org/10.1038/nrurol.2015.283

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