Currently, numerous systems exist for the identification of high-risk prostate cancer, but few of these systems can guide treatment strategies. A new stratification tool that uses common diagnostic factors can help to predict outcomes after radical prostatectomy. The tool aids physicians in the identification of appropriate candidates for aggressive, local treatment.
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References
Kane, C. J. et al. Changing nature of high risk patients undergoing radical prostatectomy. J. Urol. 177, 113–117 (2007).
Joniau, S. et al. Stratification of high-risk prostate cancer into prognostic categories: a European multi-institutional study. Eur. Urol. http://dx.doi.org/10.1016/j.eururo.2014.01.020.
Cancer Facts & Figures 2010. American Cancer Society [online], (2010).
Shariat, S. F., Karakiewicz, P. I., Roehrborn, C. G. & Kattan, M. W. An updated catalog of prostate cancer predictive tools. Cancer 113, 3075–3099 (2008).
Chughtai, B. & Mian, B. M. High risk prostate cancer: evolving definition and approach to management. Can. J. Urol. 15, 4375–4380 (2008).
Yossepowitch, O. et al. Radical prostatectomy for clinically localized, high risk prostate cancer: critical analysis of risk assessment methods. J. Urol. 178, 493–499 (2007).
Chung, B. H. The role of radical prostatectomy in high-risk prostate cancer. Prostate Int. 1, 95–101 (2013).
Donohue, J. F. et al. Poorly differentiated prostate cancer treated with radical prostatectomy: long-term outcome and incidence of pathological downgrading. J. Urol. 176, 991–995 (2006).
Lewinshtein, D., Teng, B., Valencia, A., Gibbons, R. & Porter, C. R. The long-term outcomes after radical prostatectomy of patients with pathologic Gleason 8–10 disease. Adv. Urol. http://dx.doi.org/10.1155/2012/428098.
Frank, S. J. et al. An assessment of quality of life following radical prostatectomy, high dose external beam radiation therapy and brachytherapy iodine implantation as monotherapies for localized prostate cancer. J. Urol. 177, 2151–2156 (2007).
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Buck, J., Chughtai, B. Predicting high-risk prostate cancer—a novel stratification tool. Nat Rev Urol 11, 256–257 (2014). https://doi.org/10.1038/nrurol.2014.70
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DOI: https://doi.org/10.1038/nrurol.2014.70
