Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Prostate cancer

Impact of national guidelines on brachytherapy monotherapy

New research shows that high-risk and intermediate-risk prostate cancers are being treated with brachytherapy alone, deviating from both guidelines and expert opinion. These findings should force intense introspection and scrutiny amongst clinicians, and encourage them to consider whether they are practicing evidence-based medicine.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Tseng, Y. D. et al. Impact of national guidelines on brachytherapy monotherapy practice patterns for prostate cancer. Cancer http://dx.doi.org/10.1002/cncr.28492.

  2. Frank, S. J. et al. Interstitial implant alone or in combination with external beam radiation therapy for intermediate-risk prostate cancer: a survey of practice patterns in the United States. Brachytherapy 6, 2–8 (2007).

    Article  Google Scholar 

  3. Roach, M. 3rd & Thomas, K. Overview of randomized controlled treatment trials for clinically localized prostate cancer: implications for active surveillance and the United States preventative task force report on screening? J. Natl Cancer Inst. Monogr. 2012, 221–229 (2012).

    Article  Google Scholar 

  4. Kimura, M. et al. Current salvage methods for recurrent prostate cancer after failure of primary radiotherapy. BJU Int. 105, 191–201 (2010).

    Article  CAS  Google Scholar 

  5. Mitchell, J. M. Urologists' use of intensity-modulated radiation therapy for prostate cancer. N. Engl. J. Med. 369, 1629–1637 (2013).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mack Roach III.

Ethics declarations

Competing interests

M.R. has acted as a consultant for Ferring Pharma, Millineum, and ARISTA, and received honoraria from Varian, Prostate Cancer Research Institute, Society of Uro-Oncology (Turkey), Nihon Medi-Physics, Astra-Zeneca, Astellas Pharma, e-HIMS Global Congress on Prostate Cancer, and the ESI Educational Symposium. J.J. declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Johnson, J., Roach, M. Impact of national guidelines on brachytherapy monotherapy. Nat Rev Urol 11, 195–196 (2014). https://doi.org/10.1038/nrurol.2014.50

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrurol.2014.50

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing