Predicting which patients could benefit from retroperitoneal lymph node dissection (RPLND), particularly those with locally advanced disease, could be useful. A recent article describes the formation of a predictive nomogram to predict lymph node metastasis, developed by retrospectively analysing data from 1,270 patients. Eastern Cooperative Oncology Group Performance Status, cN stage, local symptoms and LDH were associated with nodal metastasis on multivariate analysis, and the nomogram developed demonstrated a c-index of 0.89.
References
Babaian, K. N. et al. Preoperative predictors of pathologic lymph node metastasis in patients with renal cell carcinoma undergoing RPLND. J. Urol. 10.1016/j.juro.2014.10.096
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Predicting lymph node metastasis before RPLND. Nat Rev Urol 12, 3 (2015). https://doi.org/10.1038/nrurol.2014.310
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DOI: https://doi.org/10.1038/nrurol.2014.310
