In a pilot open-label study, 18 patients with chronic scrotal pain who had failed other treatment but had temporary symptom relief after standard cord block received 100 U of onabotulinumtoxinA to asses long-term pain relief. Decreases in pain measured by 10-point analogue scale pain score, scrotal tenderness by physical examination and reduction in Chronic Epididymitis Symptom Index score were reported for up to 3 months after treatment. After 6 months, most men returned to baseline levels of pain and tenderness.
References
Khambati, A. et al. OnabotulinumtoxinA (Botox) nerve blocks provide durable pain relief for men with chronic scrotal pain: a pilot open-label trial. J. Sex. Med. 10.1111/jsm.12707
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OnabotulinumtoxinA to treat chronic scrotal pain. Nat Rev Urol 11, 660 (2014). https://doi.org/10.1038/nrurol.2014.298
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DOI: https://doi.org/10.1038/nrurol.2014.298