For patients with locally advanced bladder cancer (T3b–T4 or N+ and M0) who are unfit or unwilling to undergo cystectomy, new research from a single centre has shown radical trimodal therapy can offer a survival benefit. Comprising tumour resection, platinum-based chemotherapy and radiotherapy, trimodal therapy was associated with 5-year and 10-year overall survival of 30% and 17%, respectively. These results require validation in a controlled study.
References
Baxter, B. et al. Radical trimodality therapy for patients with locally advanced bladder cancer: The British Columbia Cancer Agency experience1? Urol. Oncol. 10.1016/j.urolonc.2014.07.009
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Radical trimodal therapy as an alternative to cystectomy. Nat Rev Urol 11, 607 (2014). https://doi.org/10.1038/nrurol.2014.257
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DOI: https://doi.org/10.1038/nrurol.2014.257
