Studies have reported an increase in the use of nephron-sparing surgery (NSS) since 2002, but quality of life (QOL) may be decreased in patients managed with partial versus radical nephrectomy. These reports have highlighted existing challenges in ensuring delivery of NSS in appropriate candidates while balancing risks to mortality, morbidity and QOL.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Go, A. S., Chertow, G. M., Fan, D., McCulloch, C. E. & Hsu, C. Y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N. Engl. J. Med. 351, 1296–1305 (2004).
Huang, W. C. et al. Chronic kidney disease after nephrectomy in patients with renal cortical tumors: a retrospective cohort study. Lancet Oncol. 7, 735–740 (2006).
Campbell, S. C. et al. Guideline for management of the clinical T1 renal mass. J. Urol. 182, 1271–1279 (2009).
Patel, S. G. et al. National trends in the use of partial nephrectomy: a rising tide that has not lifted all boats. J. Urol. 187, 816–822 (2012).
Kim, S. P. et al. Contemporary trends in nephrectomy for renal cell carcinoma in the United States: results from a population based cohort. J. Urol. 186, 1779–1785 (2011).
Filson, C. P. et al. Surgeon characteristics and long-term trends in the adoption of laparoscopic radical nephrectomy. J. Urol. 185, 2072–2077 (2011).
Van Poppel, H. et al. A prospective, randomised EORTC intergroup phase 3 study comparing the oncologic outcome of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur. Urol. 59, 543–552 (2011).
Kutikov, A., Smaldone, M. C., Egleston, B. L. & Uzzo, R. G. Should partial nephrectomy be offered to all patients whenever technically feasible? Eur. Urol. 61, 732–734 (2012).
Parker, P. A. et al. Comprehensive assessment of quality of life and psychosocial adjustment in patients with renal tumors undergoing open, laparoscopic and nephron sparing surgery. J. Urol. 187, 822–826 (2012).
Smaldone, M. C. et al. Small renal masses progressing to metastases under active surveillance: a systematic review and pooled analysis. Cancer 118, 997–1006 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Smaldone, M., Kutikov, A. Assessing the management of localized kidney cancer. Nat Rev Urol 9, 186–188 (2012). https://doi.org/10.1038/nrurol.2012.45
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrurol.2012.45