Young men diagnosed with 46 XY DSD during childhood are at high risk of testicular insufficiency and micropenis persisting into adulthood, according to a recent observational study. 19 men with severe hypospadias who had been diagnosed with 46 XY DSD in childhood were re-examined at a median age of 17.6 years, when only 26% of patients had normal testicular function and 50% were >5 cm below their target adult height.
ORIGINAL RESEARCH PAPER
Blanc, T. et al. Testicular function and physical outcome in young adult males diagnosed with idiopathic 46 XY disorders of sex development during childhood. Eur. J. Endocrinol. doi:10.1530/EJE-11-0588
Rights and permissions
About this article
Cite this article
Long-term sequelae of idiopathic 46 XY disorders of sexual development. Nat Rev Urol 8, 650 (2011). https://doi.org/10.1038/nrurol.2011.189
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrurol.2011.189
