The potential of the prostate cancer antigen 3 (PCA3) urine assay to aid prostate cancer diagnosis and minimize unnecessary biopsies has been extensively studied. Results from three recent studies that compared the performance of PCA3 with PSA underscore the advancement and future challenges for this new diagnostic biomarker.
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Acknowledgements
The authors would like to thank Ms Tia Morris for editing the manuscript. The views expressed in this manuscript are those of the authors, and do not reflect the official policy of the Department of the Army, Department of Defense or the US Government.
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S. Srivastava has received grant/research support from Gen-Probe. The other authors declare no competing interests.
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Lee, G., Dobi, A. & Srivastava, S. Diagnostic performance of the PCA3 urine test. Nat Rev Urol 8, 123–124 (2011). https://doi.org/10.1038/nrurol.2011.10
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DOI: https://doi.org/10.1038/nrurol.2011.10
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