Bladder cancer

Restaging TUR reduces recurrence and progression risk

Transurethral resection (TUR) is widely used to manage early-stage bladder cancer. A recent study has confirmed that a second, or restaging, TUR is associated with a lower risk of progression and cancer-related death. Restaging TUR is therefore recommended as a standard of care in patients with stage T1 bladder cancer.

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Figure 1: Recurrence-free survival.

References

  1. 1

    Divrik, R. T., Sahin, A. F., Yildirim, U., Altok, M. & Zorlu, F. Impact of routine second transurethral resection on the long-term outcome of patients with newly diagnosed pT1 urothelial carcinoma with respect to recurrence, progression rate, and disease-specific survival: a prospective randomised clinical trial. Eur. Urol. 58, 185–190 (2010).

    Article  PubMed  Google Scholar 

  2. 2

    Kulkarni, G. S. et al. An updated critical analysis of the treatment strategy for newly diagnosed high-grade T1 (previously T1G3) bladder cancer. Eur. Urol. 57, 60–70 (2009).

    Article  PubMed  Google Scholar 

  3. 3

    Hall, M. C. et al. Guideline for the management of nonmuscle invasive bladder cancer (stages Ta, T1, and Tis): 2007 update. J. Urol. 178, 2314–2330 (2007).

    Article  PubMed  Google Scholar 

  4. 4

    Babjuk, M. et al. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder. Eur. Urol. 54, 303–314 (2008).

    Article  PubMed  Google Scholar 

  5. 5

    Brausi, M. et al. Variability in the recurrence rate at first follow-up cystoscopy after TUR in stage Ta T1 transitional cell carcinoma of the bladder: a combined analysis of seven EORTC studies. Eur. Urol. 41, 523–531 (2002).

    Article  PubMed  PubMed Central  Google Scholar 

  6. 6

    Dutta, S. C. et al. Clinical under staging of high risk nonmuscle invasive urothelial carcinoma treated with radical cystectomy. J. Urol. 166, 490–493 (2001).

    CAS  Article  PubMed  Google Scholar 

  7. 7

    Herr, H. W., Donat, S. M. & Dalbagni, G. Can restaging transurethral resection of T1 bladder cancer select patients for immediate cystectomy? J. Urol. 177, 75–79 (2007).

    Article  PubMed  Google Scholar 

  8. 8

    Herr, H. W. Restaging transurethral resection of high risk superficial bladder cancer improves the initial response to bacillus Calmette-Guerin therapy. J. Urol. 174, 2134–2137 (2005).

    Article  PubMed  Google Scholar 

  9. 9

    Grimm, M. O. et al. Effect of routine repeat transurethral resection for superficial bladder cancer: a long-term observational study. J. Urol. 170, 433–437 (2003).

    Article  PubMed  Google Scholar 

  10. 10

    Divrik, R. T., Yildirim, U., Zorlu, F. & Ozen, H. The effect of repeat transurethral resection on recurrence and progression rates in patients with T1 tumors of the bladder who received intravesical mitomycin: a prospective, randomized clinical trial. J. Urol. 175, 1641–1644 (2006).

    CAS  Article  PubMed  Google Scholar 

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Dalbagni, G. Restaging TUR reduces recurrence and progression risk. Nat Rev Urol 7, 649–650 (2010). https://doi.org/10.1038/nrurol.2010.189

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