Bladder cancer
Dietary intake of broccoli, particularly raw, is associated with a significant reduction in the risk of death from bladder cancer. Broccoli belongs to the cruciferae family, members of which are a source of chemoprotective isothiocyanates. Diet was examined among 239 patients with bladder cancer, 101 of whom subsequently died from their disease. Those patients who ate at least one serving of broccoli per month were much less likely to have died from their cancer at 8 years' follow-up.
Sexual dysfunction
Men who use erectile dysfunction drugs are at a significantly increased likelihood of contracting sexually transmitted diseases (STDs). Among American men older than 40 years, claims data from 1997 to 2006 reveals that users of these drugs had higher rates of STDs than nonusers, during both the year before and the year after initiating therapy. This difference was largely attributable to an increased rate of HIV infection. Prescription of erectile dysfunction drugs should, therefore, be accompanied by appropriate counseling.
Sexual dysfunction
Androgen blockade, to suppress nocturnal erections, is a potential treatment option for men with high-flow priapism. Among seven men who received this therapy, six reported complete resolution of priapism after a treatment period of 2–6 months; the remaining patient discontinued therapy owing to severe hot flashes. While decreased libido, fatigue and erectile dysfunction were evident during treatment, these adverse effects resolved after withdrawal of therapy.
Sexual dysfunction
Updated guidelines for the management of Peyronie's disease have been published in The Journal of Sexual Medicine following a 2-year consensus process involving experts from Europe and the USA. The evidence-based report draws on published literature and expert opinion, and concludes that the true etiology of Peyronie's disease still remains unclear. While conservative management is growing in popularity, surgery remains the mainstay of treatment of this disorder.
References
Tang, L. et al. Intake of cruciferous vegetables modifies bladder cancer survival. Cancer Epidemiol. Biomarkers Prev. 19, 1806–1811 (2010)
Jena, A. B. et al. Sexually transmitted diseases among users of erectile dysfunction drugs: analysis of claims data. Ann. Intern. Med. 153, 1–7 (2010)
Mwamukonda, K. B. et al. Androgen blockade for the treatment of high-flow priapism. J. Sex. Med. 7, 2532–2537 (2010)
Ralph, D. et al. The management of Peyronie's disease: evidence-based 2010 guidelines. J. Sex. Med. 7, 2359–2374 (2010)
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In brief. Nat Rev Urol 7, 477 (2010). https://doi.org/10.1038/nrurol.2010.133
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DOI: https://doi.org/10.1038/nrurol.2010.133