No established definition exists of therapeutic success after high-intensity focused ultrasound in patients with localized prostate cancer. A recent analysis has proposed a definition of biochemical failure for use in this setting. However, much work still needs to be done on identifying suitable predictors of clinical failure, and large-scale validation is certainly required.
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A. Pollack has received honoraria from General Electric for participating in a speakers bureau. M. Abdel-Wahab declares no competing interests.
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Abdel-Wahab, M., Pollack, A. Defining biochemical failure in patients treated with HIFU. Nat Rev Urol 7, 186–187 (2010). https://doi.org/10.1038/nrurol.2010.12
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DOI: https://doi.org/10.1038/nrurol.2010.12