Nature Reviews Neuroscience 8, 803–808 (2007)

We would like to clarify that, throughout the above article, the acronym PAT stands for 'pathologically activated therapeutics', as explained in lines 3–6 in the right-hand column on page 803.

Furthermore, we would like to clarify that the letters in the acronym UFO, as used in the last paragraph on page 804, stand for uncompetitive (U), fast (F) and off-rate (O).

Finally, in the middle column (line 19) of page 805, and in the legend to Figure 4 on page 806, the chemical formula of the nitro group was incorrect. This formula should have read: −NO2