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Genomic 'valleys of death'

This month's Genome Watch considers the features of the latest streptococcal genomes in light of a common problem — cloning bias.

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Figure 1: Clone coverage in Shewanella spp.

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DATABASES

Entrez Genome Project

Escherichia coli

S. gordonii strain substr. CH1 Challis

S. pneumoniae strain D39

S. sanguinis strain SK36

Salmonella enterica serovar Typhimurium

FURTHER INFORMATION

454 Life Sciences

Illumina

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Bentley, S. Genomic 'valleys of death'. Nat Rev Microbiol 6, 260–261 (2008). https://doi.org/10.1038/nrmicro1881

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