Abstract
With over 1 million deaths annually attributed to malaria, an effective vaccine is an urgently needed intervention. However, the various stages of the malaria parasite lifecycle have differing protective immune mechanisms and clinical endpoints, and usually different, often polymorphic, antigens. Trials using an increasing variety of vaccine platforms and antigens are under way in an attempt to achieve this long-awaited goal.
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Change history
08 March 2011
The authors wish to acknowledge that they were supported by funding from the UK National Institute for Health Research (NIHR) Oxford Biomedical Research Centre programme at the time of writing. The authors apologize for the oversight.
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The authors thank the UK National Institute for Health Research Oxford Biomedical Research Centre programme for funding.
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Todryk, S., Hill, A. Malaria vaccines: the stage we are at. Nat Rev Microbiol 5, 487–489 (2007). https://doi.org/10.1038/nrmicro1712
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DOI: https://doi.org/10.1038/nrmicro1712
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