This month's column looks at a recent comparative analysis of three members of the Rickettsiales that are all causative agents of human ehrlichiosis.
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References
Dunning Hotopp, J. C. et al. Comparative genomics of emerging human ehrlichiosis agents. PLoS Genet. 2, e21 (2006).
Chakravortty, D. & Hensel, M. Inducible nitric oxide synthase and control of intracellular bacterial pathogens. Microbes Infect. 5, 621?627 (2003).
Lin, M. & Rikihisa, Y. Ehrlichia chaffeensis and Anaplasma phagocytophilum lack genes for lipid A biosynthesis and incorporate cholesterol for their survival. Infect. Immun. 71, 5324?5331 (2003).
Cerdeño-Tárraga, A. et al. Extensive DNA inversion in the B. fragilis genome control variable gene expression. Science 307, 1463?1465 (2005).
Acknowledgements
The author thanks Dr Stephen Bentley, The Wellcome Trust Sanger Institute, for helpful discussions.
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DATABASES
Entrez Genome Project
FURTHER INFORMATION
Ehrlichial Research Laboratory at the Ohio State University, College of Veterinary Medicine
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Crossman, L. Budget genomes. Nat Rev Microbiol 4, 326–327 (2006). https://doi.org/10.1038/nrmicro1396
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DOI: https://doi.org/10.1038/nrmicro1396
