The winning image of this month's Nature Cell Biology and Nature Reviews Molecular Cell Biology 'Cell of the Month' competition was submitted by Matthew Daniels (Hutchison/Medical Research Council (MRC) Research Centre, Cambridge, UK (mjd46@hermes.cam.ac.uk)). When all chromosomes are attached to the spindle and under tension, they become arranged in a structure known as the metaphase plate. When two metaphase plates occur in a single cell, they become orientated perpendicularly to each other, seen here in the shape of an 'X'.
The image shows a three-dimensional reconstruction of a HeLa cell that was stained for actin (blue), kinetochores (green) and DNA (red). The image was obtained using a laser scanning microscope (Zeiss LSM 510 META), and was rendered using Zeiss LSM Image Browser Software. Bar, 5 μm.
The winner would like to acknowledge the University of Cambridge M.B./Ph.D. programme and the MRC for funding this work.
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Daniels, M. Image competition. Nat Rev Mol Cell Biol 5, 517 (2004). https://doi.org/10.1038/nrm1442
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DOI: https://doi.org/10.1038/nrm1442