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The next steps for genomic medicine: challenges and opportunities for the developing world


This is a historical moment on the path to genomic medicine — the point at which theory is about to be translated into practice. We have previously described human genome variation studies taking place in Mexico, India, Thailand, and South Africa. Such investments into science and technology will enable these countries to embark on the path to the medical and health applications of genomics, and to benefit economically. Here we provide a perspective on the challenges and opportunities facing these and other countries in the developing world as they begin to harness genomics for the benefit of their populations.

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This project was funded by Genome Canada through the Ontario Genomics Institute. The Indian Council of Medical Research provided in kind co-funding for this research. The McLaughlin–Rotman Centre for Global Health, Program on Life Sciences, Ethics and Policy is primarily supported by Genome Canada through the Ontario Genomics Institute, the Ontario Research Fund, and the Bill and Melinda Gates Foundation. Other matching partners are listed at The McLaughlin–Rotman Centre for Global Health web site. A.S.D. and P.A.S. are supported by the McLaughlin Centre for Molecular Medicine. P.A.S. is supported by a Canadian Institutes of Health Research Distinguished Investigator award.

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Correspondence to Abdallah S. Daar.

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eVOC software program

Genome-based Research and Population Health International Network (GRaPH-Int)

Human Genome Diversity Project of Iran (HGDPI)

International Conference on Harmonization (ICH)

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South African National Bioinformatics Institute (SANBI)

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US National Office of Public Health Genomics

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Hardy, BJ., Séguin, B., Goodsaid, F. et al. The next steps for genomic medicine: challenges and opportunities for the developing world. Nat Rev Genet 9, S23–S27 (2008).

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