Liver X receptors (LXRs) are nuclear receptors that have a key role in the regulation of lipid homeostasis in tissues such as the liver, brain and intestine. In their Review on p433, Hong and Tontonoz highlight how LXRs could be targeted for the treatment of lipid disorders, including atherosclerosis and Alzheimer's disease.
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Recent patents related to liver X receptors. Nat Rev Drug Discov 13, 409 (2014). https://doi.org/10.1038/nrd4354
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DOI: https://doi.org/10.1038/nrd4354