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Hypertension

Arteriovenous anastomosis—next panacea for hypertension?

The ROX CONTROL HTN study demonstrated the efficacy of arteriovenous coupler therapy in patients with resistant hypertension. However, one-third of the patients developed late ipsilateral venous stenosis, which required venoplasty or stenting. Future research is needed to identify the risk–benefit ratio of this new approach.

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Figure 1: Net mean difference in office and 24 h blood pressure between the arteriovenous coupler treatment group (n = 44) and the control group (n = 39) in the ROX CONTROL HTN trial.4

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Acknowledgements

F.M. is supported by a grant from Deutsche Hochdruckliga, the German Hypertension League, and by Deutsche Gesellschaft für Kardiologie, the German Society of Cardiology. M.B. is supported by a grant from Deutsche Forschungsgemeinschaft, the German Research Foundation (KFO 196).

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Correspondence to Felix Mahfoud.

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Mahfoud, F., Böhm, M. Arteriovenous anastomosis—next panacea for hypertension?. Nat Rev Cardiol 12, 197–198 (2015). https://doi.org/10.1038/nrcardio.2015.24

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