Randomized trials of open versus endovascular repair (EVR) of abdominal aortic aneurysm have demonstrated the short-term superiority of EVR, but have raised questions about the long-term durability of this approach. The final report from the OVER trial now demonstrates that EVR is the treatment of choice for morphologically suitable aortic aneurysms.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Lederle, F. A. et al. Long-term comparison of endovascular and open repair of abdominal aortic aneurysm. N. Engl. J. Med. 367, 1988–1997 (2012).
Brown, L. et al. The UK EndoVascular Aneurysm Repair (EVAR) trials: randomised trials of EVAR versus standard therapy. Health Technol. Assess. 16, 1–218 (2012).
De Bruin, J. L. et al. Long-term outcome of open or endovascular repair of abdominal aortic aneurysm. N. Engl. J. Med. 362, 1881–1889 (2010).
Becquemin, J. P. et al. A randomized controlled trial of endovascular aneurysm repair versus open surgery for abdominal aortic aneurysms in low- to moderate-risk patients. J. Vasc. Surg. 53, 1167–1173.e1 (2011).
Karthikesalingam, A. & Holt, P. in Oxford Textbook of Vascular Surgery (Oxford University Press, Oxford, in press).
Schermerhorn, M. L. et al. Endovascular vs open repair of abdominal aortic aneurysms in the Medicare population. N. Engl. J. Med. 358, 464–474 (2008).
Moll, F. L. et al. Management of abdominal aortic aneurysms clinical practice guidelines of the European Society for Vascular Surgery. Eur. J. Vasc. Endovasc. Surg. 41, S1–S58 (2011).
Karthikesalingam, A. et al. Heterogeneity in surveillance after endovascular aneurysm repair in the UK. Eur. J. Vasc. Endovasc. Surg. 42, 585–590 (2011).
Karthikesalingam, A. et al. Systematic review and meta-analysis of duplex ultrasonography, contrast-enhanced ultrasonography or computed tomography for surveillance after endovascular aneurysm repair. Br. J. Surg. 99, 1514–1523 (2012).
Holt, P. J. et al. Aortic rupture and sac expansion after endovascular repair of abdominal aortic aneurysm. Br. J. Surg. 99, 1657–1664 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
M. M. Thompson has received honoraria from Cook Medical, Endologix, and Medtronic; has acted as a consultant for Endologix and Medtronic; and has received research support from Cook Medical and Medtronic. A. Karthikesalingam declares no competing interests.
Rights and permissions
About this article
Cite this article
Karthikesalingam, A., Thompson, M. Repair of infrarenal aortic aneurysm—the debate is OVER. Nat Rev Cardiol 10, 122–124 (2013). https://doi.org/10.1038/nrcardio.2013.4
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrcardio.2013.4
This article is cited by
-
Cardiac rehabilitation versus standard care after aortic aneurysm repair (Aneurysm CaRe): study protocol for a randomised controlled trial
Trials (2015)
-
A systematic review and meta-analysis indicates underreporting of renal dysfunction following endovascular aneurysm repair
Kidney International (2015)
