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Biocomputing

DNA computes a square root

Complex molecular circuits with reliable digital behaviour can be created using DNA strands.

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Figure 1: Key features of the DNA circuits made by Qian and Winfree1.

References

  1. Qian, L. L. & Winfree, E. Science 332, 1196–1210 (2011).

    CAS  Article  Google Scholar 

  2. Kaplan, S., Bren, A., Zaslaver, A., Dekel, E. & Alon, U. Mol. Cell 29, 786–792 (2008).

    CAS  Article  Google Scholar 

  3. Yurke, B., Tuberfield, A. J., Mills, A. P., Simmel, F. C. & Neumann, J. L. Nature 406, 605–608 (2000).

    CAS  Article  Google Scholar 

  4. Seelig, G., Soloveichik, D., Zhang, D. Y. & Winfree, E. Science 314, 1585–1588 (2006).

    CAS  Article  Google Scholar 

  5. Yin, P., Choi, H. M. T., Calvert, C. R. & Pierce, N. A. Nature 451, 318–322 (2008).

    CAS  Article  Google Scholar 

  6. Martin, A. J. & Nystrom, M. Proc. IEEE 94, 1089–1120 (2006).

    Article  Google Scholar 

  7. Shapiro, E. & Benenson, Y. Sci. Am. 294, 44–51 (May 2006).

    CAS  Article  Google Scholar 

  8. Leinser, M., Bleris, L., Lohmueller, J., Xie, Z. & Benenson, Y. Nature Nanotech. 5, 666–670 (2010).

    Article  Google Scholar 

  9. Venkataraman, S., Dirks, R. M., Ueda, C. T. & Pierce, N. A. Proc. Natl Acad. Sci. USA 107, 16777–16782 (2010).

    CAS  Article  Google Scholar 

  10. Wagner, N. & Ashkenasy, G. Chem. Eur. J. 15, 1765–1775 (2009).

    CAS  Article  Google Scholar 

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Correspondence to Yaakov Benenson.

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Benenson, Y. DNA computes a square root. Nature Nanotech 6, 465–467 (2011). https://doi.org/10.1038/nnano.2011.128

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  • DOI: https://doi.org/10.1038/nnano.2011.128

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