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Protein-nanoparticle interactions

What does the cell see?

Fluorescence correlation spectroscopy is used as a quantitative method to understand the binding and exchange behaviour of proteins on the surfaces of nanoparticles.

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Figure 1: Nanoparticle–protein complexes as seen by the cell.

References

  1. Lynch, I., Dawson, K. A. & Linse, S. Sci. STKE 327, 14–20 (2006).

    Google Scholar 

  2. Cedervall, T. et al. Proc. Natl Acad. Sci. USA 104, 2050–2055 (2007).

    Article  CAS  Google Scholar 

  3. Cedervall, T. et al. Angew. Chem. Int. Ed. 46, 5754–5756 (2007).

    Article  CAS  Google Scholar 

  4. Hellstrand, E. et al. FEBS J. 276, 3372–3381 (2009).

    Article  CAS  Google Scholar 

  5. Ehrenberg, M. S., Friedman, A. E., Finkelstein, J. N., Oberdörster, G. & McGrath, J. L. Biomaterials 30, 603–610 (2009).

    Article  CAS  Google Scholar 

  6. Nel, A. E. et al. Nature Mater. 8, 543–557 (2009).

    Article  CAS  Google Scholar 

  7. Faunce, T. A., White, J. & Matthaei, K. I. Nanomed. 3, 859–866 (2008).

    Article  CAS  Google Scholar 

  8. Röcker, C., Pötzl, M., Zhang, F., Parak, W. J. & Nienhaus, G. U. Nature Nanotech. 4, 577–580 (2009).

    Article  Google Scholar 

  9. Wang, B., Zhang, L., Bae, S. C. & Granick, S. Proc. Natl Acad. Sci. USA 105, 18171–18175 (2008).

    Article  CAS  Google Scholar 

  10. Dawson, K. A., Salvati, A. & Lynch, I. Nature Nanotech. 4, 84–85 (2009).

    Article  CAS  Google Scholar 

  11. Lynch, I. & Dawson, K. Nano Today 3, 40–47 (February/April, 2008).

    Article  CAS  Google Scholar 

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Lynch, I., Salvati, A. & Dawson, K. What does the cell see?. Nature Nanotech 4, 546–547 (2009). https://doi.org/10.1038/nnano.2009.248

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