Human neural stem cells could be used to treat many diseases, but a major problem with this approach is that these cells give rise to few neurons in the brain. Now a new priming method increases production of neurons after implantation, including the elusive cholinergic neurons.
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Blackshaw, S., Cepko, C. Stem cells that know their place. Nat Neurosci 5, 1251–1252 (2002). https://doi.org/10.1038/nn1202-1251
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DOI: https://doi.org/10.1038/nn1202-1251