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Toward a molecular biology of memory: the light's coming on!

Nature Neuroscience volume 1, pages 543–545 (1998)Cite this article

Abstract

Transgenic mice with a CREB-dependent reporter gene are used to show that contextual fear conditioning activates CRE-mediated transcription in CA1 of the hippocampus.

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Figure 1: Summary of the CREB pathway that has been implicated in long-term memory formation.
Figure 2: CREB-mediated transcription occurs when an associative memory forms in the hippocampus.

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Authors and Affiliations

  1. Cold Spring Harbor Laboratory, Cold Spring Harbor, 11724, New York, USA

    Tim Tully

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  1. Tim Tully
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Tully, T. Toward a molecular biology of memory: the light's coming on!. Nat Neurosci 1, 543–545 (1998). https://doi.org/10.1038/2780

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