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Epigenetic control of myelin repair

Nature Neuroscience volume 11, pages 987–988 (2008)Cite this article

Although the CNS has a robust innate ability to repair demyelinated axons, this capacity appears to dissipate with age. A study in this issue suggests that epigenetic processes participate in myelin repair and that the epigenetic response is less dynamic in older individuals.

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Figure 1: Diagram depicting the epigenetic control of OPC maturation.

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Authors and Affiliations

  1. Department of Neurology, The author is at the Jack Miller Center for Peripheral Neuropathy, University of Chicago, 5841 South Maryland Ave., MC2030, Chicago, Illinois 60637-1470, USA. bpopko@uchicago.edu,

    Brian Popko

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Popko, B. Epigenetic control of myelin repair. Nat Neurosci 11, 987–988 (2008). https://doi.org/10.1038/nn0908-987

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