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RNA decay back in play

Lasting synaptic plasticity requires precise local regulation of protein expression. A recent paper reports that the postsynaptic activity–induced arc mRNA is a target for rapid degradation by the 'nonsense-mediated decay' pathway.

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Figure 1: Exon-junction complex.
Figure 2: Nonsense-mediated decay.

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Peebles, C., Finkbeiner, S. RNA decay back in play. Nat Neurosci 10, 1083–1084 (2007). https://doi.org/10.1038/nn0907-1083

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